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脉冲参数可控经颅磁刺激 ELEVATE TMS for cTMS

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简介 TMS技术革命性突破:脉冲波形可自由控制调整
品牌 ROGUE RESEARCH
型号 cTMS
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产品详情参考文献相关视频资料下载

Elevate TMS


TMS技术革命性突破:脉冲波形可自由控制,面向未来5到10年的下一代TMS技术。


Elevate TMS 脉冲参数可控磁刺激器 (cTMS)为用户提供了对磁刺激脉冲宽度及脉冲波形各个参数前所未有的控制和自由,以修改和适应其TMS脉冲宽度和形状的所有方面。


这些新的可控脉冲参数对于研究人员探索TMS如何在神经元水平上与大脑相互作用,以及提供一种强大的、可重复的兴奋或抑制效果至关重要。


Elevate TMS的仪器设计灵感来自于哥伦比亚大学的Angel Peterchev博士的新颖工作,其独特的系统架构由两个电容器和一个复杂的开关系统组成。


与传统的TMS设备不同,Elevate TMS能够在高频率(高达1kHz)连续生成接近矩形的电场脉冲,并允许直接控制脉冲的宽度、形状、幅度和定向性。


直观的控件和用户界面


Elevate TMS系统采用直观且用户友好的触摸屏界面,允许快速和精确地调整所需的脉冲参数和研究范例。

Elevate TMS用户界面


多种线圈设计和选项可用


Elevate TMS系统的所有线圈均具有可拆卸的线圈手柄,使研究人员可以更改配置以适应其所有喜好。


所有线圈都包括不同的电感,以扩展Elevate TMS系统提供的cTMS脉冲范围。内置的线圈跟踪器安装还意味着Elevate TMS系统可以与Brainsight TMS Navigation软件无缝集成,进行神经导航TMS会话。




对于使用计算建模技术的研究人员,Elevate TMS线圈的B场已完全进行了三维映射,可用于E场建模研究。


产品特点:


完全可定制的脉冲形状

由于独特的系统架构,Elevate TMS可以传递无数的TMS脉冲。可以操纵TMS脉冲的所有方面,以针对不同神经元。改变TMS脉冲的宽度和形状的能力使研究人员能够探索前所未有的选项。双相、多相、阶梯和非对称脉冲形状可以作为单向和双相rTMS、theta-burst和Quadri pulse协议进行传递。

直观便捷的控制界面

一个大触摸屏界面被用来控制Elevate TMS。所有参数,包括刺激类型、设置脉冲形状和控制M比率都托管在Elevate TMS专有软件上。

多种规格线圈

Rogue Research提供了一系列具有低、中、高电感的ElevateTMS兼容线圈。


参考文献:

  1. Pulse width biases the balance of excitation and inhibition recruited by transcranial magnetic stimulation. Ricci Hannah, Lorenzo Rocchi, Sara Tremblay, Eleanor Wilson, & John C. Rothwell. Brain Stimulation. May 2020

  2. Longer cTMS pulse width switches 1 Hz inhibitory motor cortex rTMS aftereffects to excitation. I. Halawa, Y. Shirota, A. Neef, M. Sommer, & W. Paulus. Brain Stimulation. March 2019

  3. Effects of pulse width, waveform and current direction in the cortex: A combined cTMS-EEG study. Casula EP, Rocchi L, Hannah R, & Rothwell JC. Brain Stimulation. October 2018

  4. TMS of primary motor cortex with a biphasic pulse activates two independent sets of excitable neurones. Sommer M, Ciocca M, Chieffo R, Hammond P, Neef A, Paulus W, Rothwell JC, & Hannah R. Brain Stimulation. May 2018

  5. Enhancement of Neuromodulation with Novel Pulse Shapes Generated by Controllable Pulse Parameter Transcranial Magnetic Stimulation. Goetz SM, Luber B, Lisanby SH, Murphy DL, Kozyrkov IC, Grill WM, & Peterchev AV. Brain Stimulation. January 2016

  6. Strength-Duration Relationship in Paired-pulse Transcranial Magnetic Stimulation (TMS) and Its Implications for Repetitive TMS. Shirota Y, Sommer M, & Paulus W. Brain Stimulation. September 2016

  7. Effect of coil orientation on strength–duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulation. Kevin D’Ostilio, Stefan M.Goetz, Ricci Hannah, Matteo Ciocca, Raffaella Chieffo, Jui-Cheng A. Chen, Angel V. Peterchev, & John C. Rothwell. Clinical Neurophysiology. January 2016



  1. Pulse width biases the balance of excitation and inhibition recruited by transcranial magnetic stimulation. Ricci Hannah, Lorenzo Rocchi, Sara Tremblay, Eleanor Wilson, & John C. Rothwell. Brain Stimulation. May 2020

  2. Longer cTMS pulse width switches 1 Hz inhibitory motor cortex rTMS aftereffects to excitation. I. Halawa, Y. Shirota, A. Neef, M. Sommer, & W. Paulus. Brain Stimulation. March 2019

  3. Effects of pulse width, waveform and current direction in the cortex: A combined cTMS-EEG study. Casula EP, Rocchi L, Hannah R, & Rothwell JC. Brain Stimulation. October 2018

  4. TMS of primary motor cortex with a biphasic pulse activates two independent sets of excitable neurones.Sommer M, Ciocca M, Chieffo R, Hammond P, Neef A, Paulus W, Rothwell JC, & Hannah R. Brain Stimulation. May 2018

  5. Enhancement of Neuromodulation with Novel Pulse Shapes Generated by Controllable Pulse Parameter Transcranial Magnetic Stimulation. Goetz SM, Luber B, Lisanby SH, Murphy DL, Kozyrkov IC, Grill WM, & Peterchev AV. Brain Stimulation. January 2016

  6. Strength-Duration Relationship in Paired-pulse Transcranial Magnetic Stimulation (TMS) and Its Implications for Repetitive TMS. Shirota Y, Sommer M, & Paulus W. Brain Stimulation. September 2016

  7. Effect of coil orientation on strength–duration time constant and I-wave activation with controllable pulse parameter transcranial magnetic stimulation.Kevin D’Ostilio, Stefan M.Goetz, Ricci Hannah, Matteo Ciocca, Raffaella Chieffo, Jui-Cheng A. Chen, Angel V. Peterchev, & John C. Rothwell. Clinical Neurophysiology. January 2016