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Deymed DuoMAG XT rTMS 高频重复经颅磁刺激器

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简介 支持高频重复脉冲刺激
品牌 Deymed
型号 DuoMAG XT
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脑盒科技为DuoMAG系列经颅磁刺激系统中国总代理,欢迎致电400-880-8790了解详情。


DuoMAG XT系列重复经颅磁刺激系统功能强大、配置灵活,在可以满足多种重复磁刺激神经调控研究需要。凭借优异的性能和全新设计的交互界面,便利化的设计,DuoMAG已经日益成为国际上众多实验室的新选择。


DuoMAG XT rTMS系统提供的重复经颅磁刺激(rTMS) ,可根据刺激强度、线圈方向和频率增加或降低大脑皮层兴奋性。


BrainBox提供三种不同的迭代和多种不同的配置,专注于用户友好性,专有软件包含一个强大的5kHz肌电图软件,用于记录和分析MEP,被试数据和会话历史可以保存,导出和匿名,一个专用的协议构建器允许为研究应用创建rTMS序列和theta burst刺激协议。


DuoMAG XT100能够提供满足在100Hz时提供高达40%的刺激器总能量输出,theta burst刺激模式时可以提供高达67%的刺激器能量输出。DuoMAG XT35和XT10刺激器能够分别提供35Hz和10Hz的rTMS。


Brainbox了解在有限工作空间内灵活解决方案的需求,因此很自豪地提供三种不同配置的DuoMAG XT。对于那些更喜欢便携解决方案的用户来说,DuoMAG的TMS推车配有线圈臂,刺激器和可选的触摸屏电脑可以很容易地在不同地点之间移动。最后,平衡电磁操作线圈臂,在较长的rTMS会话中可以保持线圈位置稳定。

DuoMAG XT Configurations

所有DuoMAG XT刺激器都可以通过TTL、USB 2.0或以太网连接进行外部控制,用于灵活的研究应用。


所有的DuoMAG系统都可以通过线圈手柄上的内置控制来完全控制刺激强度和触发(如下图所示)。


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Features:



自定义刺激协议编辑器

 直观的软件可以轻松控制受试者数据库,包括完全匿名数据和导出刺激历史。用于计算静息电机阈值 (RMT) 和活动电机阈值 (AMT) 的专用屏幕,能够添加/编辑光标以突出显示幅度/延迟。

DuoMAG XT 的自定义协议编辑器可以自定义所有刺激参数,包括重复序列、刺激频率、突发频率和电机阈值百分比的刺激。

自动 MEP 振幅计算

 在单脉冲模式下传递TMS脉冲后,DuoMAG EMG软件配置为记录和绘制由此产生的电机诱发电位(MEP)的最高和最低峰值。可以添加延迟信息,并在必要时操作游标。

MEP数据被存储并用于在提供重复TMS(rTMS)协议时计算刺激器强度。

所有MEP数据和信息都可以以多种格式导出,以供离线分析。

自动AMT计算

 在计算主动运动阈值 (AMT) 时,首先需要记录参与者的**自愿等长收缩 (MVIC),然后再执行收缩到该值的目标百分比。

DuoMAG软件的内置功能使研究人员能够校准这两种反应,并记录有源运动阈值,同时为参与者显示颜色编码的目标值。

外部通信

通过 TTL 输入/输出触发器和 USB 支持外部通信。

多模式应用

DuoMAG XT rTMS系统通过整个Deymed产品系列提供无缝集成,用于真正的多模式研究。Deymed EEG,EMG / MEP系统可以控制TMS设备的强度和触发,使用户能够将注意力集中在参与者而不是硬件上。

多种配置

 三种不同的重复刺激器选项和两种不同的推车选项使我们能够根据任何预算或要求指定系统。独立系统可用于桌面工作区,推车使系统能够安装在手推车上,便于携带,以便在不同的站点使用,并且可以指定可选的平衡电磁操作臂,以确保在会话中消除线圈运动。这种灵活性,加上广泛的线圈类型,使DuoMAG系统在定制方面无与伦比。



部分已发表论文:


  1. Is the vertex a good control stimulation site? Theta burst stimulation in healthy controls. Dominik Pizem, Lubomira Novakova, Martin Gajdos & Irena Rektorova. Journal of Neural Transmission. 25/01/2022

  2. Hebbian Activity-Dependent Plasticity in White Matter. Lazari, A., Salvan, P., Cottaar, M., Papp. D., Rushworth, M., and Johansen-Berg, H. Cell Reports. December 2021

  3. Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus. Mareike A. Gann, Bradley R. King, Nina Dolfen, Menno P. Veldman, Marco Davare, Stephan P. Swinnen, Dante Mantini, Edwin M. Robertson & Geneviève Albouy. Scientific Reports. October 2021

  4. Functional Connectivity at Rest between the Human Medial Posterior Parietal Cortex and the Primary Motor Cortex Detected by Paired-Pulse Transcranial Magnetic Stimulation. Rossella Breveglieri, Sara Borgomaneri, Matteo Filippini, Marina De Vitis, Alessia Tessari, Patrizia Fattori. Brain Sciences. October 2021

  5. Development of an Advanced Sham Coil for Transcranial Magnetic Stimulation and Examination of Its Specifications. Mayuko Takano, Jiri Havlicek, Dan Phillips, Shinichiro Nakajima, Masaru Mimura, and Yoshihiro Noda. Journal of Personalized Medicine. October 2021

  6. Seizure risk with repetitive TMS: Survey results from over a half-million treatment sessions.. Joseph J. Taylor, Noam G. Newberger, Adam P. Stern, Angela Phillips, David Feifel, Rebecca, A. Betensky, Daniel Z. Press. Brain Stimulation. August 2021

  7. Impact of one HF-rTMS session over the DLPFC and motor cortex on acute hormone dynamics and emotional state in healthy adults: a sham-controlled pilot study. Blair T. Crewther, Wiktoria Kasprzycka, Christian J. Cook & Rafał Rola. Neurological Sciences. May 2021

  8. Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus. Mareike Gann, Bradley King, Nina Dolfen, Menno Veldman, Marco Davare, Stephen Swinnen, Dante Mantini, Edwin Robertson & Genevieve Albouy. Neuroimage. May 2021

  9. Low-frequency rTMS to the parietal lobe increases eye-movement carryover and decreases hazard rating. P.J. Hills, G. Arabaci, J. Fagg, C. Thompson & R. Moseley. Neuropsychologia. May 2021

  10. Short-Term Immobilization Promotes a Rapid Loss of Motor Evoked Potentials and Strength That Is Not Rescued by rTMS Treatment. Christopher Gaffney, Amber Drinkwater, Shalmali Joshi, Brandon O’Hanlon, Abbie Robinson, Kayle-Anne Sands, Kate Slade, Jason Braithwaite and Helen Nuttall. Frontiers in Human Neuroscience. April 2021

  11. Natural oscillation frequencies in the two lateral prefrontal cortices induced by Transcranial Magnetic Stimulation. Antonino Vallesi, Alessandra Del Felice, Mariagrazi Capizzi, Alessandra Tafuro, Emanuela Formaggio, Patrizia Bisiacchi, Stefano Masiero, Ettore Ambrosini. Neuroimage. February 2021

  12. Motor resonance is modulated by an object’s weight distribution. Guy Rens, Jean-Jacques Orban de Xivry, Marco Davare, Vonne van Polanen. Neuropsychologia. 2021

  13. Identification of psychiatric disorder subtypes from functional connectivity patterns in resting-state electroencephalography. Yu Zhang, Wei Wu, Russell T. Toll, Sharon Naparstek, Adi Maron-Katz, Mallissa Watts, Joseph Gordon, Jisoo Jeong, Laura Astolfi, Emmanuel Shpigel, Parker Longwell, Kamron Sarhadi, Dawlat El-Said, Yuanqing Li, Crystal Cooper, Cherise Chin-Fatt, Martijn Arns. Nature Biomedical Engineering. October 2020

  14. Enhancing cognitive training effects in Alzheimer’s disease: rTMS as an add-on treatment. Bagattini Chiara, Zanni Mara, Barocco Federica, Caffarra Paolo, Brignani Debora, Miniussi Carlo, Defanti Carlo Alberto. Brain Stimulation. September 2020

  15. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, and Marco Davare. Journal of Neurophysiology. August 2020

  16. Sensorimotor expectations bias motor resonance during observation of object lifting: The causal role of pSTS. Guy Rens, Vonne van Polanen, Alessandro Botta, Mareike A. Gann, Jean-Jacques Orban de Xivry and Marco Davare. Journal of Neuroscience, JN-RM-2672-19. April 2020

  17. An electroencephalographic signature predicts antidepressant response in major depression. Wei Wu, Yu Zhang, […] Amit Etkin. Nature Biotechnology. February 2020

  18. Theta-burst transcranial magnetic stimulation induced cognitive task-related decrease in activity of default mode network: An exploratory study. Lubomira Novakova, Martin Gajdos, & Irena Rektorova. Brain Stimulation. January 2020

  19. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, & Marco Davare. bioRxiv. December 2019

  20. Restoring tactile sensations via neural interfaces for real-time force-and-slippage closed-loop control of bionic hands. Loredana Zollo, Giovanni Di Pino, Anna L. Ciancio, Federico Ranieri, Francesca Cordella, Cosimo Gentile, Emiliano Noce, Rocco A. Romeo, Alberto Dellacasa Bellingegni, Gianluca Vadalà, Sandra Miccinilli, Alessandro Mioli [...] and Eugenio Guglielmelli. Science Robotics. February 2019

  21. Non-invasive stimulation of the auditory feedback area for improved articulation in Parkinson's disease. Lubos Brabenec, Patricia Klobusiakova, Marek Barton, Jiri Mekysk, Zoltan Galaz, Vojtech Zvoncak, Tomas Kiska, Jan Mucha, Zdenek Smekal, Milena Kostalova, & Irena Rektorova. Parkinsonism & Related Disorders. October 2018

  22. Intermittent Theta Burst Stimulation Over Ventral Premotor Cortex or Inferior Parietal Lobule Does Not Enhance the Rubber Hand Illusion. Alessandro Mioli, Marco D’Alonzo, Giovanni Pellegrino, Domenico Formica, and Giovanni Di Pino. Frontiers in Neuroscience. 2018

  23. Combining Robotic Training and Non-Invasive Brain Stimulation in Severe Upper Limb-Impaired Chronic Stroke Patients. Vincenzo Di Lazzaro, Fioravante Capone, Giovanni Di Pino, Giovanni Pellegrino, Lucia Florio, Loredana Zollo, Davide Simonetti, Federico Ranieri, Nicoletta Brunelli, Marzia Corbetto, Sandra Miccinilli, Marco Bravi, & Stefano Milighet. Frontiers in Neuroscience. October 2016

  24. Recognition and Processing of Visual Information after Neuronavigated Transcranial Magnetic Stimulation Session. Wiktoria Kasprzycka, Magdalena Ligia Naurecka, Bartosz Michał Sierakowski, Paulina Putko, Zygmunt Mierczyk, Grzegorz Chabik, Stanisław Dec, Stefan Gaździński and Rafał Rola. Brain Sciences. September 2022